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KMID : 1001920120520060558
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Journal of Korean Neurosurgical Society
2012 Volume.52 No. 6 p.558 ~ p.560
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Experience with 5-Aminolevulinic Acid in Fluorescence-Guided Resection of a Deep Sylvian Meningioma
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Chae Michael P
Song Sang-Woo
Park Sung-Hye
Park Chul-Kee
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Abstract
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The 5-aminolevulinic acid (5-ALA)-induced tumor fluorescence is a useful intraoperative marker for the diagnosis and the detection of various malignancies, but its use in meningioma is only reported infrequently. In meningioma, a complete resection of the tumor mass is crucial for the prevention of recurrence and postoperative morbidities. Deep sylvian meningioma is a rare type of meningioma where complete tumor removal is complicated by its deep anatomical location and close involvement with the middle cerebral artery. From our experience, 5-ALA-mediated fluorescence facilitated a safe excision whilst preserving critical neurovascular structures. To our best knowledge, this is first report from use of 5-ALA in a deep sylvian meningioma.
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KEYWORD
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5-aminolevulinic acid, Resection, Deep sylvian meningioma, Meningioma without dural attachment
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